you could find a caves boss in the basement. uses as his main mechanic, Killing or damaging enemies spawns various poops, which add to his collection. If you touch an enemy in that time, Isaac will pick it up and slam it on the ground, killing it and sending a shockwave around the impact, In the brief period while holding the enemy you can move a target to decide where it lands, Actually does work on bosses! treasure room, item room pool, white, Upon use, consumes a coin and deals damage to everything in the room, Damage dealt is equal to your tear damage * 2 + 10, REPENTANCE - Damage buffed, previously it was damage * 2. Killing a petrified enemy will freeze it. If any enemies walk into its path, it will deal 7 contact damage every 7 frames, Nearby enemies will be forced to target and attack it, If the obstacle it is attached to is destroyed then it will continue rolling in the direction it was previously travelling until it meets another wall or obstacle, Causes your bombs to explode into 2-4 tiny bombs, The smaller bombs deal half damage and have a smaller explosion area. When used, this card drops all of your hearts (including non-red hearts), coins, keys and bombs on the floor, This effect is done in the most efficient way possible - e.g. Mulligan can be hit by enemy projectiles, making him a good shield, Enemies will sometimes target the Mulligan if he is closer, * item room, treasure room, item room pool, sad, baby, lumpy, brown, pink, When used, makes Isaac leap in the air, similar to the leaper enemies, Maintains momentum if you are already moving in the same direction, If you already have an item which gives you flying, this item becomes a dash effect instead, Can be used in the Isaac boss fight to jump over the beams of light he spawns, * library pool, library room, book room pool, item room, treasure room, item room pool, Can be negated with Black Candle, Bad Gas - Isaac farts, poisoning enemies around him, Bombs are key - Switches number of bombs and keys, Explosive Diarrhea - Spawns five live troll bombs behind Isaac, one per second, Full Health - Restores all your empty red heart containers, Health Down - -1 HP. Poison deals 5 damage initially and then 3.5, UNLOCK: Unlock this item by beating Blue Womb (Hush) with Isaac, REPENTANCE - GB Bug is now a thrown projectile, activated by double tapping an attack button. Stat Up becomes Stat Down), Any 'Stat down' pills you take give you a permanent +0.6 Damage Up (Horse pills +1.2), Most other pills spawn a black heart when used, including R U A Wizard?, Amnesia, Bad Trip, ?? Collection Page (Repentance) - Binding of Isaac: Rebirth Wiki By Jack This guide will give you the BASICS of all items. This one will be a hidden question mark, Allows you to see what both items are on alternative path floors (Downpour/Dross, Mines/Ashpit, Gehenna/Mausoleum), UNLOCK: Unlock this trinket by defeating challenge #40 (Seeing Double). the lost item pool, gold, orange, yellow, cross, pope, hat, A familiar the follows Isaac and fires random tears, Rainbow Baby's tears can choose from any of the other familiars, such as homing, spectral, tar shots etc, * item room, treasure room, item room pool, purple, Upon use, opens all closed doors in the current room, including the ones which require a key to enter and secret room doors, Can be used to open the golden door that appears in the Dark Room or the Chest, Cannot be used to escape the Mom's Foot boss, open angel/devil rooms, or open the door to the Blue Womb floor, UNLOCK: Unlock this item by collecting both Key Pieces #1 & #2 for the first time, * key master pool, key beggar pool, key judgement pool, item room, treasure room, item room pool, After killing a 15 enemies, Blood Puppy transforms into an aggressive version that will also attack Isaac by charging at him. As Azazel they fire brimstone and as The Forgotten they use a bone club, At the beginning of all future floors, two portals will appear, that can take you to either the Boss room (Red portal), Item room (Yellow portal) or Secret room (Blue portal), After Chapter 3 (The Depths floors) only one portal will spawn, Portals disappear if you leave the starting room, Every time an enemy dies, a random familiar spawns where it was killed for the rest of the room, The familiar cannot move, but continues to do its usual abilities, Possible familiars include: Abel, Boiled Baby, Brother Bobby, Sister Maggy, Little Steven, Demon Baby, Multidimensional Baby, Freezer Baby, Rotten Baby, Harlequin Baby, Ghost Baby, Guardian Angel, Lil Brimstone, Robo-Baby and Seraphim, Every 5 seconds you become spiky for a second, becoming immune and dealing 40 contact damage to any enemies that touch you, The effect is indicated by 4 white flashes, where the item activates on the 4th flash, If timed well, can be used to enter curse rooms and open spiky chests without taking damage. arrow, Causes your friendly blue spiders and flies to become bigger and do x2 more damage, Allows Mom's Wig to spawn a maximum of 10 spiders at once instead of 5, Fly and spider familiars become stronger similar to BFFS, * shop room pool, shop item pool, blue, fat, Two items now spawn after beating a boss fight and the boss rush, however only one can be taken, The additional item will pick from the Boss Item Pool, Unlocked by donating to the donation machine in the shop, UNLOCK: Unlock this item by donating 50 pennies to the Shop, * shop room pool, shop item pool, white, question mark, square, theres options, * shop room pool, shop item pool, purple, paper, ticket, Isaac can now hold 2 cards or runes at once. *, brown, red, tup, carton, box, golden chest pool, gold chest pool, Item Pool: Boss Room, Gold/Stone Chest, Mom's Chest, *, white, necklace, grey, gray, moms pearls, mom pearls, The Car Battery causes your spacebar item to activate twice on each use, For example, with Yum Heart you would heal 2 full red hearts instead of 1, Upon use, gives you a duplicate of each familiar you have for the current room, It will not 'double' your familiars as the tagline suggests - if you have 2 of one kind, it will only give you an extra one, If the familiar only appears when taking damage (i.e. Every playable character in The Binding of Isaac: Repentance has a "tainted" version. Pretty Fly gives a Big Fan item rather than a fly orbital, UNLOCK: Unlock this by defeating Mega Satan as Tainted Eve, 1 Dot - Rerolls all of your items. Based on the Steam Workshop mod created by Ratlah, UNLOCK: Unlock this item by sleeping in 10 different beds, When used, this item will sacrifice up to 2 of your familiars (chosen at random), and spawn a random Devil Room item for each familar sacrificed this way, In addition to the familiars, any blue flies or spiders will be converted to 1 coin each, If Guardian Angel, Sworn Protector, or Seraphim is sacrificed, Satan will be extra happy and reward you with 2 black hearts, Incubus won't be sacrificed if you're playing as Lilith, If used while you have no familiar, this item will do nothing and won't consume the item, Added as part of the Afterbirth+ Booster Pack #5. Binding of Isaac . The Mega Mush is a new mushroom-type item in The Binding Of Isaac: Repentance and, like the other mushrooms, significantly affects the player's stats. item room pool, red, boom, tnt, * item room, treasure room, item room pool, wooden, cross, brown, Isaac can now hold two trinkets at the same time, Drops a random trinket on the floor when picked up, Allows you to pick up more trinkets while also holding The Tick, * shop room pool, shop item pool, purple, pink, bag, All of Isaac's bombs now leave a poison effect on any enemies within the blast radius, As well as dealing the standard 60 damage for a bomb, it will apply a Damage over Time effect that does 4 or 6 damage per tick, Has a chance to drop from the Super Sloth miniboss fight. pills in one run, A familiar which follows Isaac and, upon taking damage, will spawn a charmed enemy that will fight for you, When the charmed enemy is spawned the egg will crack, but regenerate in the next room, UNLOCK: Unlock this item by spawning 3 charmed enemies in a single room, Flat Stone causes your tears to bounce across the room, Whenever a tear bounces, it deals splash damage to nearby enemies for 25% of your tear damage, Added as part of the Afterbirth+ Booster Pack #5. This will deviate you from the alt path if you are currently on it, Since this item resets your stats, this item can remove Broken Hearts, UNLOCK: Unlock this item by defeating Greedier Mode as Jacob & Esau, Upon use, allows you to consume 1 key and fire it at an enemy, piercing enemies and dealing significant damage, The damage done by the key projectile pierces through enemies and scales with your damage upgrades (x5 damage + 30), Keys fired by this item can open locked doors/chests, secret rooms and destroy objects in the room, such as rocks, Cannot be used if you don't have any keys, Enemies killed by Sharp Key have a ~10% chance to spawn random items that appear in a chests. One of the best parts of the Binding of Isaac is the huge number of item interactions and synergies you can get by combining certain items, however they don't always work as expected. now allows the player to influence the teleport direction (using the direction Isaac is moving upon activating the item), * item room, treasure room, item room pool, blue remote, robot, When used as the Keeper, one coin HP is restored, Has a chance to drop from the Super Lust miniboss fight, Item Pool: Item Room, Super Lust Miniboss, * item room, treasure room, item room pool, the lost item pool, maggy, starting, * item room, treasure room, item room pool, dungeon room, blood challenge room, arena pool, When used, this item will rewind time and put you back in the previous room, in the same state you were in at that moment, This means any damage taken or consumables used in the current room will be reset back to the previous state, Can be used to check the contents of an Item Room without affecting Planetarium spawn chances, Glowing Hour Glass has no cooldown, but can only be used 3 times per floor (as of 1.7.9 update), Recharge time: None (Max 3 use per floor), Item Pool: Item Room, Shop, Greed Mode Item Room, * hourglass, hour glass, egg, timer, blue, brown Glowing Hourglass, Gives Isaac a large white halo around him, that deals a bit of damage to any enemies in contact with the ring, Every time an enemy bullet enters the ring, there is a chance it will reflect a homing tear back at the enemy, Coins have a 10% chance to be replaced with Sack. Clots returning back to Eve deal 3x damage as they suck back in, The type of heart consumed to create a clot will give it different abilities: Soul Hearts = More health, Black Hearts = Dark Matter effect, Eternal Hearts = Sacred Heart effect, Gold Hearts = Midas Touch effect, Bone Hearts = Compound Fracture effect, Rotten Hearts = Less health, Tainted Eve starts with this item, but can be used by any character after unlocking it and finding it in the item room, UNLOCK: This item comes along with Tainted Eve. The chance for this effect to activate depends on your Luck stat. If used with Brimstone you have a 100% chance to fire a laser out the back of your head, * dungeon room, blood challenge room, arena pool, item room, treasure room, item room pool, Buy The Binding of Isaac: Rebirth | Xbox Basement 1, Cathedral, Sheol etc. Smaller enemies spawn 2-3 tears, and bosses spawn a maximum of 16, Tears from this effect maintain tear modifiers and status effects that Isaac currently has, Isaac doesn't take damage from the tears created by this item, Every time you take damage, a tiny Isaac familiar will spawn, which follows you and shoots tears at nearby enemies that deal 1.3 Damage, The mini-Isaacs stay with you between floors, but can die if they take too much damage, Maximum number of mini-Isaacs is 16 at one time, Mini-Isaac's keep some of the abilities and appearance that Isaac has - e.g. Join. or the path they take (My Reflection, Tiny Planet etc. The spear cannot be thrown like Mom's Knife but deals damage while it is in contact with an enemy, *, grey, silver, sword, dagger, blade, knife, Tears now have a random chance to become sticky bombs, which will attach to enemies and explode after a few seconds, The bomb explosion deals your tear damage + 60, REPENTANCE - Explosivo tears now deal damage upon impact, When picked up, drops between 1-6 random pickups on the floor, Causes all item pedestals to be chosen from a random item pool instead of the pre-defined ones which normally exist, Fixed item drops won't be replaced - e.g. debug 4 - +40 damage to the hero's tears. REPENTANCE - The Inner Eye now causes less of a decrease in rate of fire than previously, and now has a tighter spread. They do not block enemy shots, UNLOCK: Unlock this item by defeating The Beast as Tainted Lilith, Isaac builds rage each time you clear a new room. ?, Satan and The Lamb as Tainted Magdalene, The first time you pick this trinket up, the heart container will be filled. devil room pool, devil deal, grey, gray, hood, Isaac now has a small chance to create friendly attack spiders everytime he fires a tear, Can create up to a maximum of 5 spiders in the room at one time, The Hive Mind item allows Mom's Wig to spawn a maximum of 10 spiders at once, and increases their damage, The chance to create a spider is affected by your luck stat and at +10 Luck it will activate every time, * dungeon room, blood challenge room, arena pool, item room, treasure room, item room pool, Each tick of poison damage is equal to your normal tear damage, Some random tears will gain the Rubber Cement effect and become bouncy, Grants +0.25 Speed, +0.75 Range, +0.1 Shot Speed, +0.2 Tears, +0.5 Damage and +1 Luck when Isaac's active item is fully charged, Infinite use items such as Potato Peeler count as charged and provide the bonus from this trinket, Grants +0.5 Speed, +1.5 Range, +0.3 Shot Speed, +0.4 Tears, +1.5 Damage when Isaac's active item is completely uncharged, One-time use items such as Mama Mega count as uncharged and provide the bonus from this trinket, Gives you another secret room on each new floor while held, Does not spawn more than one super secret room, only the normal secret room, *, purple, torn, ripped, paper, page, poster, When you have the same amount of coins, bombs and keys, half consumables turn into their doubled version, This effect works for any number of consumables, including 0 and 99, as long as the count for coins/keys/bombs is equal, Every time you take damage you have a very small chance to spawn a random pedestal item, When the effect triggers, the trinket is destroyed, Every time you take damage you have a very small chance to spawn the Lunch item, which gives +1 HP up, When the effect triggers, this trinket is destroyed, Increases the radius of any creep you produce, While held, any damage taken remove red hearts first, before soul hearts, black hearts and rotten heart damage, While at 1/2 of a red heart, it will begin to remove your other hearts again, UNLOCK: Unlock this item by beating Greedier mode with Eve, The Walnut has a chance to break when taking damage from an explosion. Cannot be rerolled by 4-pip dice rooms and Spindown Dice, Clearing a room will spawn an extra reward, however only one can be picked up - the other one will disappear, UNLOCK: Unlock this item by defeating the The Beast as Isaac, Every half red heart you pick up gives a small but permanent stat increase, Randomly picks between +0.10 Damage Up, +0.05 Tears Up, +0.15 Range Up, +0.02 Speed Up, +0.1 Luck Up, +0.02 Shot Speed Up per half red heart, UNLOCK: Unlock this item by defeating The Beast as Magdalene, This item causes Devil deals to cost money instead of hearts, and shop items to cost hearts instead of money, Shop items cost heart containers, and pickups have spikes around them, The Devil deal conversion rate is 1 heart container to 15 coins, Devil deal items can be on discount similar to the shop, making it 1 heart container = 7 coins instead, UNLOCK: Unlock this item by defeating The Beast as Cain, Every time you enter a devil room and choose not to take an item, you get +1 Damage Up upon entering the next floor, The effect is shown via a cross above Isaac's head. This mechanic is very useful on Greed and Greedier modes, UNLOCK: Unlock this item by defeating Delirium in The Void floor with Keeper, *, orange, brown, yellow, gold, coin, cent, Upon use this item hurts Isaac without actually taking health away, allowing you to activate any items which trigger when taking damage without losing health, UNLOCK: Unlock this item by defeating Delirium on The Void floor with Eve, When used, this item permanently removes one of your red heart containers and gives you a flat +0.2 Damage Up, the Anemic effect (+1.5 Range Up + red creep trail) and a Cube of Meat, The Anemic effect will only last for the current room, but the Cube of Meat and Damage Up are both permanent, Only works for red hearts and has no effect when used if you only have soul/black hearts, Has no recharge time and can be used as often as you like, It is possible to generate multiple meatboys by stacking more than 4 Cubes of Meat, When used, this item gives you the effect of a random item for the rest of the room, Using this item multiple times in the same room will replace the previous item's effect with a new one, Certain items can be activated with this item which have unexpected effects and many items will do nothing, Items do not grant consumable drops which would normally occur when that item is picked up, Most flight-granting items have cosmetic effects only, and will not allow you to fly, Items that usually give HP up will not give extra health when gained from Metronome, UNLOCK: Unlock this item by defeating Greedier Mode with Eden, This dice allows you to press the Drop key to cycle between all possible dice effects and pick one to use, Charge time scales based on the chosen dice, updating every time you use it, Possible dice include: D1, D4, D6, D8, D10, D12, D20, D100. UNLOCK: Unlock this trinket by collecting three of the following in the same run: Magic 8 Ball, Tiny Planet, Crystal Ball, Star of Bethlehem or any of the Astrology-related items (e.g. ?s soul, blue baby's soul, blue babys soul, When you kill an enemy, you have a chance to get +0.5 damage up for the current room, UNLOCK: Unlock this item by beating the Dark Room with Samson, *, hair, pony, tail, brown, red, samsons lock, Gives a 25% chance to reveal map icons at the start of a new floor (The same effect as the Compass), UNLOCK: Unlock this item by beating the Chest with Cain, When you kill an enemy, you have a chance to spawn a transparent Dead Bird familiar, The Dead Bird familiar deals 2 damage per tick to enemies while in contact with them, UNLOCK: Unlock this item by beating the Isaac boss with Eve, *, grey, gray, black, striped, eves bird foot, REPENTANCE - No longer replaces chests that have already spawned, UNLOCK: Unlock this item by beating Ultra Pride, * northernlion, drop the left hand, paw, bloody, bleeding, grey, gray, While held, tinted rocks and rocks with a crawlspace below them will flash white every 10 seconds, *, grey, gray, silver, lump, metal, stone, Turns all troll bombs into bombs which you can pick up and use, Super Troll bombs turn into 1+1 free double bomb pickups, Gives your tears a random worm effect every few seconds, The possible tear effects include: Whip Worm, Ring Worm, Wiggle Worm, Flat Worm, Hook Worm, Pulse Worm, Tape Worm and Lazy Worm, While held, Tape Worm doubles your range stat and halves your tear height stat, Every time you get hit, you have a chance to activate the D6, D20, D8, D10 or D12 effect. A familiar fly that moves in a straight line and attaches itself to the first obstacle or wall it comes into contact with in each room. 146. This can be anything that would normally drop from a chest including pedestal items, When used, this item causes Isaac to become humongous for 30 seconds, While huge, Isaac is invincible and can crush objects, doors and enemies, For the duration of the effect this gives you a x4 Damage Multiplier and +2.0 Range Up, but your rate of fire goes way down. After killing a 25 more enemies, it transforms again dealing 15 damage and destroying obstacles it charges into. This guide will be updated when new items get added. Holding this trinket increase that chance by +15%. Cosmetic change only. The Binding of Isaac is a randomly generated action RPG shooter with heavy Rogue-like elements. ), Keeps the chance at 100% even after entering and leaving the angel room, meaning the door will not close after visiting, Makes it impossible to find Devil Rooms again, unless you find a way to remove or reroll this item away, or find the Duality item, UNLOCK: Unlock this item by defeating Delirium in The Void floor with Maggy, A sack familiar that drops a sack every 5 or 6 rooms cleared (alternates between 5 and 6), UNLOCK: Unlock this item by defeating Greedier Mode as Cain, * back in black, ac/dc, bag, brown, pouch, pocket, bulge, Gives you an extra heart container for every 25 coins you are currently holding, up to a maximum of 4 extra HP at 99 coins held, If your coin counter goes below the required amount for a heart container, you will lose it again, This item works for the Keeper, allowing him to exceed his usual 2 health containers, However, if Keeper drops to under 2 health coins as a result of Greed's Gullet, he is unable to use a HP Up to increase his health back to 2, and has to regain the lost coins to do so, UNLOCK: Unlock this item by beating Challenge #35 (Pong), *, dollar, cash, sack, bag, pouch, greeds gullet, greed gullet, Gives you a random chance while firing tears to also fire a creep shot, which deals double your tear damage and places white creep on the floor infront of you that slows enemies down if they walk through it, Unlike some similar tear effects, your luck stat does not alter the chance for this effect to activate, A creep shot is also fired in a random direction after taking damage, While firing tears you have a 5% chance to fire a void tear.