This is my first contribution to CSN, of many i hope and prayer and just wanted to relate a part of my fight against this terrible killer. You may temporarily stop certain medicines or supplements that increase bleeding, like aspirin. CEA elevation; inflammatory response; oxaliplatin. can stress raise cea levels - justripschicken.com Thank you and I will let you know when I have some news to share. It can also be increased during pregnancy. Does anyone have a similar experience to this? Specialists in a laboratory analyze the blood to check for CEA. Few people are aware that exercise, especially intense activity, can significantly alter certain laboratory tests. No but his office called today. Healthcare providers dont use the CEA test to screen for or diagnose cancer. Compared to the median level of 26.8 ng/mL, patients with CEA levels of >69 ng/mL were at a significantly elevated risk for progression. I'm not in a position to second guess your Docs or mine, but colon cancer often metastesizes to lung, liver, peritoneum, pancreas, where it can still elevate CEA. However, I just had a CT scan a week ago and it showed a couple of new tumors in my lung that weren't there in February. Inflammation can affect tumor development and progression in addition to the response to therapy. Carcinoembryonic antigen blood . Federal government websites often end in .gov or .mil. I am sure we will just be coming up with a plan of some sort. Carcinoembryonic antigen (CEA) can be higher than the normal range in a blood test for the following reasons: Cancer: It is a tumor marker and raises in the presence of a malignant tumor. Ng SL, Burns WI, Snyder RD, Newnham GM, McLachlan SA, Liew D, Dowling AJ. I wish you all the best and negative cancer findings! As a stageI, there is a ~10% chance of 5yr recurrence, but as a stageI whose CEA never returned to normal (<3), I've got a ~30% chance of recurrence. My oncologist tends to rely more on scans and blood work and my overall well being and keep me grounded to not get too excited Many healthy people have normal level of tumor makers, which is called normal range, reference range or reference interval on lab reports. Has anyone experienced fluctuation in their results? My oncologist orders a PET. CEA at surgery was around 8. I had 2 follow ups since the surgery. This has been going on for the past 2 years. My follow up is every three months bloodwork and every six months CT scans. 2022 Aug 25;9:945433. doi: 10.3389/fmed.2022.945433. You dont need any special preparations for a CEA blood test or a pleural fluid test. 2018-04-27. I am guessing you have seen this details (based on your knowledge above), but just a bit of support for you. CEA levels can be elevated by several sorts of non-cancerous conditions, but note that colon cancer is not a single monoilithic thing - it includes several distinct types and perhaps uknown distinctions. These cookies ensure basic functionalities and security features of the website, anonymously. As far as questions to ask your dr, I might ask if the test should be done again. People with many types of cancers can have levels that are higher than 3 ng/mL. Don't let these numbers frighten you - at this level, they are meaningless, even if they trend up. The study, which followed 96 patients with chronic lymphocytic leukemia (CLL), found that those who felt more stress and anxiety about about their condition also had a higher volume of cancer cells in their blood and higher blood levels of markers for advanced disease. We all get caught up in the stats, it is difficult not to when you are dealing with this. It helps to talk with others about their experiences. But a rise in CEA level four to six weeks after initiation of therapy doesnt necessarily mean treatment failure, relapse or recurrence. @spedteacher At the request of @hopeful33250 I am responding to you. It also ups your risk for digestive problems and depression. If you have CEA levels this high and you also have symptoms of cancer, it strongly suggests the cancer has not been removed successfully after treatment. We did blood screening through the Mayo clinic and they came back that I had a predisposition for polyposis. Jul 28, 2013 10:23 PM. I am aware(via reading others' posts that in the scheme of things, my CEA number is not a huge "red flag or alarm" but it is to me. I hope you have someone in your life holding your hand right now and helping you get through this traumatic time. @colleenyoung @diannechildress My CEA has been staying between 1.7 and 2.4 since my colon cancer was removed b on 1/16. CR.I'm so sorry about your Mom even if you didn't have cancer that would have been so stressful to go through but you have mets to cope with on top of losing one of the most important people in your life. How should I prepare for a Carcinoembryonic antigen test? What can cause a false positive CEA? He said all along that polyps typically don't cause CEA elevation. Our findings clearly indicated that immobilization stress results in enhanced serum CEA level whether the stress is acute or chronic. Dropped to 3.7. I need to find a way to deal with this issue. A singular increase in CEA levels is not significant. Understandably, any rise in your CEA level can cause a. It's common for people to assume that their hemorrhoids are the cause of painful bowel movements. As far as questions to ask your dr, I might ask if the test should be done again. Elevated levels of CEA occur when the CEA is higher than 3 ng/mL. J Natl Compr Canc Netw. My CEA number from the recent blood test showed my CEA to be 4.9(which the company puts an average range of 0.2.5 or up to 3.0. These are usually less than 10 ng/ml. Discussion. Some forms of CRC are unlikely to be associated with elevated CEA, and also those same types have poor prognosis, however in others types of CRC, elevated CEA does correlate with poorer outcomes and suggests metastitisis to liver or lung (primarily, but others ) . Last year, during my normal checkup, CEA was run again and to my surprise.9.7. So what's left? Policy. Different labs may have slightly different references ranges and clinicians may consider higher thresholds depending on the individual circumstances. It can be safely used in pregnant/breastfeeding women as well as in children. During a CEA blood test, your healthcare provider: If your healthcare provider needs to take samples of other body fluids, they: A CEA blood test usually takes less than five minutes. Required fields are marked *. And no, I am not a smoker. That could mean that stress not only wakes up dormant tumor cells but also . We did colonoscopies for almost 7 years and my gastroenterologist decided that we should remove the remainder of the colon to eliminate any further polyps. I have had my mammogram done and it is clear, I dont have any more colon so it cant be colon cancer, I had a hysterectomy when I was in my 20s so that rules out ovarian cancer. The https:// ensures that you are connecting to the I did read the article you mentioned above. http://www.cochrane.org/CD011134/COLOCA_detecting-recurrent-colorectal-cancer-testing-blood-carcino-embryonic-antigen-cea. Yeah - there are several studies that show a pretty high false-positive rate for CEA in ppl like us who have had a resection. When my CEA went from .5 to .6 I about freaked out. This includes some antibiotics, antacids, and cholesterol medications. Others have used other blood tests to supplement CEA such as CA19-9 or CA125. He said he's had patients which had CEAs as high as 20 end up not having any cancer recurrence. Mine hadnt gone over 3 until I had the remaining colon removed. In contrast, the progression risk appeared to be lower for patients with CEA levels lower than 26.8 ng/mL, but a significance level was not reached. Tumor markers are substances that are either made by cancer or made by the body in response to cancer. I guess we'll see if my oncologist is correct in two weeks. I've had Stage IIa with a resection of the ascending and part of transverse colon, all lymph nodes (22) were clean. I can certainly understand your concern about the increase", "@spedteacher At the request of @hopeful33250 I am responding to you. False-positive CEA elevations have been reported to occur in smokers and in patients with nonmalignant conditions, including gastrointestinal disease (eg, inflammatory bowel disease, pancreatitis, liver disease, diverticulitis, hepatitis, peptic ulcers, biliary obstruction, cirrhosis), lung disease (eg, chronic Inserts a small needle into one of your veins, usually in your arm. Your provider will combine it with physical examination and imaging as needed. Thus, we suggest that exercise for 2-3 days per week decreases the expression of CEA and improves body condition, without loading fatigue or stress, which may contribute to preventing cancer in the elderly women. It sounds like you are feeling good otherwise, but your concern is about the increase in the CEA numbers. Understandably, any rise in your CEA level can cause a great deal of anxiety for you and everyone close to you. I am IV B. Cancer antigen 125 (also known as carbohydrate antigen 125 or CA 125) is an antigen first identified by Bast et al. I hope you can get some rest and time to restore yourself now. Thanks for telling us about the results of the CT scan. Does that fit in you case? CEA levels will generally return to normal between one and four months after the cancer has been successfully removed. We all ride that roller coaster one way or another, but your numbers seem great to me, so try to relax..Dave. In adults, an abnormal level of CEA may be a sign of cancer. If you have values that are that high, it doesnt mean you have cancer. Thank you for your kind words. "Hello @spedteacher, Welcome to Mayo Clinic Connect. I was wondering if anyone else has had this problem? It statistically suggest a much higher probability of recurrence. Please meet @travelgirl @martid @ilene1 @soul @brglight @nannytart @bush @sallyg @starrlight and @joannem. I just starting to comprehend all this and dont understand all of it but as long as blood levels are good and liver functions are normal. I had melanoma on my right forearm, which resulted in a surgery leaving a 32 stitch scar. This past April I was in to my oncologist for my check-up and my level has increased to 6.1. Patient Guide to Tumor Markers | OncoLink Consistent with our finding, there are reports suggesting that stress can increase tumor growth and tumor marker expression [26, 27]. Cleveland Clinics Robert J. Tomsich Pathology & Laboratory Medicine Institute touches virtually every patient at Cleveland Clinic and thousands of patients across the world. My concern is regarding my CEA levels. The cookies is used to store the user consent for the cookies in the category "Necessary". I was diagnosed in 2009 but it was only stage 2. Here we go again. What could be going on?? Six patients had at least three CEA values and four were included in the study. 8600 Rockville Pike 5 months later, I had a bowel blockage due to scar tissue and had more of the small bowel and transverse colon removed. Any help with this would be greatly appreciated. Our findings clearly indicated that immobilization stress results in enhanced serum CEA level whether the stress is acute or chronic. So we're all scratching our heads wondering what is going on. CEA levels that start low and later increase can point to cancer that has come back after a patient has completed treatment. Your CEA levels are all low. Consistent with . He also said he's not convinced the CEA spike last year when the polyp with appendicial cancer was found was due to that cancer. Thanks in advance. The CEA test is only one piece of the puzzle. Hi everyone. I am going to see my GP in an hour. CEA dropped back down to 5.4 and 5.2. Frequent question: How accurate is CEA for colon cancer? Went back to my CRC surgeon and he did a right hemicolectomy to be sure nothing gets left behind. Who Can Benefit From Diaphragmatic Breathing? I can certainly understand your concern about the increase in the CEA number. 2010 May;21(5):1013-9. doi: 10.1093/annonc/mdp449. CEA levels in ovarian cancer: Link, tests, and more - Medical News Today It does not store any personal data. Ok. Clinical signs and imaging modalities also play a role in the final assessment. But I've NEVER had a CEA below 1.0. CEA does not tell you what is going on, only that something might be going on and might be worth checking out. Making me a bit nervous, but will see next blood test. He wanted to clean the cecum area of my colon to look before pulling the scope out. Welcome to the forums, sorry you have to be here, but this is a good place with good people. That comes back clear. I will keep everyone posted on the outcome of both the CT scan and my flexoidoscoy. You tend to wait for the "other shoe to drop.". No follow-ups for me until May - 8 months post-op. Study Suggests Link Between Stress, Cancer Returning - NCI So what's going on? Theres no magic number or threshold for a CEA test that points to cancer. Serum CEA levels fluctuate over time in healthy individuals, and the intraindividual variation has been reported to be about 30% . Cochrane reviews (highly respected meta-studies that are often used as guidelines) suggest a CEA of 10 as a trigger to start looking for recurrence. Had a lymphedectomy(?) At this point I have a 10% chance of being here in three years based on stats. These levels are considered abnormal. CEA = Create Elevated AnxietyMy CEA has run the range from 0.57 to about 17.0. He doesn't like what he's hearing and orders a PET/CT. A CA 125 test isn't accurate enough to use for ovarian cancer screening in general because many conditions can increase the level of this protein. I stopped having it checked in 2013 as it was not a good indicator for me. Thank you so much. Performance cookies are used to understand and analyze the key performance indexes of the website which helps in delivering a better user experience for the visitors. Take a deep breath - you're okay! But stress isn't [] The results of my CT scan were good. I was diagnosed with colon cancer in 2009. When I changed to a different lab fro my blood work, my CEA went from .5 to 1.6 (yes, I freaked out); but then I was told that my blood had been tested at a different lab, which tests come out higher. Oxaliplatin has been shown to cause an inflammatory response which appears to be one of the mechanisms of toxicity and high CEA levels have been correlated with increased inflammation. Stress also causes an increase in blood sugar, which means the vessels can't dilate or contract to better control blood flow. Our findings clearly indicated that immobilization stress results in enhanced serum CEA level whether the stress is acute or chronic. Hello, I am new to this group. Thank you for all the repsonses regarding CEA blood test. What is the normal range for CEA blood levels? I would be surprised if that fact didn't send all your numbers soaring. This must be confirmed , as the CEA test by itself is not specific enough to substantiate a recurrence of a cancer. Caffeine, Alcohol, and Tobacco. A carcinoembryonic antigen (CEA) test measures CEA, a specific blood protein. They are indicators that something might be wrong and so shouldn't be ignored if the numbers spike. I have to say I'm not happy about the failure of my CEAs to drop into the normal range (<3.1 on this test). What is considered a high tumor marker number? I'm so sorry about your mom. He immediately said, that's not good. If the other tumor markers are down (which they are), then he is not concerned.
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